Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Does plaquenil cause high blood pressure Chloroquine wiki Drug interations plaquenil Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil serious side effects What can Hydroxychloroquine Plaquenil do to my eyes?, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Sudden blurry vision with plaquenil have floaters Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. Common and Rare Side Effects for Plaquenil Oral. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. The goal with ocular screening for the side effects of Plaquenil is to find the damage at the earliest stage to reduce the amount of vision loss. The risk is low in the beginning and increases over time as the drug collects in the retinal pigment epithelial layer. The risk of damage is dose related. RARE BUT SERIOUS side-effects include Changes to the Eyes – Plaquenil can rarely cause changes to the retina in the back of the eye. Patients should get their eyes checked by an eye doctor every year to make sure the medicine isn’t affecting the back of the eye.