Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Is chloroquine safe during pregnancy Chloroquine base molecular weight Chloroquine blood stage Chloroquine dosing for lupus retina Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The AVISE HCQ test is available as a venous test and via a AVISE ® Touch low volume capillary device test. Clinical Utility The AVISE HCQ test is intended for use in patients on hydroxychloroquine PLAQUENIL therapy, after steady state approx. 90-120 days, to help assess the following Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Oct test for plaquenil Spectral domain optical coherence tomography as an., Retinal Physician - Hydroxychloroquine Maculopathy An. 200 plaquenil day lupusQuinacrine and hydroxychloroquine lupus panniculitisPlaquenil birthDifference between primaquine and chloroquineCan you take hydroxychloroquine while breastfeeding If you just did one test, an OCT for example, which is very specific at picking up toxicity, it might be that you’re seeing age-related issues that just look like HCQ toxicity. Despite Plaquenil dosing recommendations, retinal toxicity.. Hydroxychloroquine Test - Hydroxychloroquine Side Effects - Exagen Inc.. How to Succeed in Plaquenil Screenings. Problems with Plaquenil Use Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Before beginning treatment with plaquenil, the doctor will perform a baseline eye examination and the following tests Dilated Retinal Examination, Retinal Photography, Visual Field Test, OCT. The risk of developing retinopathy increases with the length of time plaquenil has been taken and the dosage prescribed. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity.