Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine eye test Plaquenil and laser eye surgery Is there a generic for plaquenil drug After the first couple months I noticed that my hair was "shedding" a lot. When I brought the concern up to my rheumatologist he said that the hair loss was "probably" due to lupus itself & not the result of taking plaquenil! I found his response strange given the fact that I wasn't losing hair prior to taking plaquenil. Yes, Plaquenil can cause alopecia or hair loss. Plaquenil hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil can change the pigmentation in the skin, so it would stand to reason that it can do the same with hair. I have experienced the change in pigmentation on my legs. It looks like I have a huge bruise on the back of my leg which extends from the calf to the ankle. I call it a perma-bruise. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil cause hair loss Tips to Prevent Hair Loss in Lupus Patients, Does plaquenil cause hair loss? - Plaquenil cause blindnessHydroxychloroquine plaquenil weight lossHydroxychloroquine plaquenil adverse effectsCan hydroxychloroquine cause diarrhea In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Plaquinel changes hair color?" Lupus Community - Support Group. Lupus Hair Loss Pictures, Symptoms, Treatment, Prevention.. Hair loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Psoriatic arthropathy Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Hair loss w/ plaquenil temporary adjustment or permanent. However, it seems like there are a lot of posts on here and elsewhere about people losing hair because of Plaquenil. Does anyone know if this happens if it's a temporary adjustment to the medication similar to when you shed hair a few months after having a baby or something more.