Although it is uncommon, lupus can also attack a patient’s liver, causing a more pronounced elevation in liver enzymes, such as ASTs and ALTs. When this happened to me, my symptoms included pervasive malaise, nausea, itching, and worsening of my overall health and lupus activity. Cost of plaquenil in us Psoriasis and plaquenil Plaquenil induced psoriasis Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. You should talk with your healthcare provider prior to taking hydroxychloroquine sulfate Plaquenil ® if you have Psoriasis Liver disease, such as liver failure, cirrhosis, or hepatitis Alcoholism G-6-PD glucose-6-phosphate dehydrogenase deficiency Any other allergies, including allergies to food, dyes, or preservatives. Jun 27, 2014 In this group, 6 patients had a concurrent liver involvement with the diagnosis of SLE, and it occurred later during an exacerbation of the disease in the remaining 5 patients 19. Clinical manifestations were as follows hepatomegaly n = 4, jaundice n = 4, abdominal pain n = 3, ascitis n = 2. They consulted and referred me to a gastroenterologist. My family doctor was persistent in finding an answer, and wouldn’t let my rheumatologist rest until they found one. Plaquenil and liver failure Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Precautions and Warnings With Hydroxychloroquine Drug interations plaquenilHydroxychloroquine 20 mg Hydroxychloroquine is an antimalarial drug. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Challenge of liver disease in systemic lupus erythematosus.. Common and Rare Side Effects for Plaquenil Oral. Aug 30, 2011 HCQ is cleared by the kidneys and thus renal disease increases the risk of toxicity. Therefore, both dosage and screening frequency may need to be adjusted. Tamoxifen use used in breast cancer treatment increases the risk of toxicity approximately 5 fold 8. The mechanism of this linkage is not understood. The injections are better and longer lasting. Get liver tested monthly. If mthx doesn't get it under control, ask for a biologic. That works for most people. If you are mild, you might want to try Plaquenil first. The big thing, is to stop the deformities as quickly as possible, and get the disease into remission. The sooner the better results. Plaquenil belongs in a class of medications known as disease-modifying antirheumatic drugs DMARDs. It is most often prescribed to patients who try and fail biologic DMARDs biologic DMARDs, also known as biologics, are medications made up of living matter such as human cells, bacteria and yeast, cannot tolerate biologics, or for those who.