I've been on it for 10 months and I noticed within a couple of weeks that I was pretty itchy. I recently went to the dermatologist for a rash and he said that my rash was from scratching. Hydroxychloroquine combination arimidex Chloroquine blood stage Hi, I started taking Plaquenil on June 24th and for the last four or 5 days have had horrible itching. No rash just all over itching. My Rhuemy told me to stop taking it until all itching symptoms were gone, then wait another week and start up again with 1 pill 200mg a day instead of 2. Serious skin reactions can occur during treatment with this medicine. Check with your doctor right away if you or your child have any of the following symptoms while using this medicine blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. By reducing inflammation, hydroxychloroquine can decrease pain, swelling and stiffness of joints, and improve or clear some rashes. Which skin conditions are treated with hydroxychloroquine? These include I have to tell you though that I was bad, I would scratch and scratch at them and caused an ugly rash and broke skin so your dermy is right. I think the itch has become worse since I started on Cymbalta. I had some itching in the beginning of taking Plaq mostly on my upper arms but it eventually went away. Hydroxychloroquine itchy skin Chloroquine-induced Pruritus, Hydroxychloroquine Oral Route Precautions - Mayo Clinic Chloroquine schizontsHow to reduce stomach discomfort with plaquenilPlaquenil and parkinson'sCost of plaquenil in usChloroquine er derived vaculation Yes with plaquenil generic, I have itching, intense I could scratch through my skin. But it does calm down. I also get weird rashes but I get those from the Lupus. I find the disease is being treated and the med is attacking the inflammation, so one of the first places inflammation shows up is the skin since it is the largest organ we have. Plaquenil and itching -. Hydroxychloroquine Skin Support. Hydroxychloroquine Indications, Side Effects, Warnings -. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. For people with skin problems This drug may.