Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Endometriosis plaquenil Antacid and plaquenil Plaquenil while pregnant risks Do not take Plaquenil after the expiry date printed on the bottle. It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date. If diarrhea came back I had to back off and wait a week to add it again. After 2 months I could take the full dose BUT I can't take it as one tablet in a.m. and one in p.m. I have to break it up and take it 4 times a day to get in the normal 2 200mg tablets per day. The dizziness got better although I still have it a little from time to time. I was just about to write a post on about this then i saw this post, iv been on plaquenil for about 4 years and looking back about 2 years r more my moods have been all over the place one day im fine and happy next day like today all i want to do in hide in my bed and cry, is this a lupus thing r am i depressed? / Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil cause dizziness after 2 years Plaquenil Drug and Medication User Reviews on RxList, Plaquenil and dizziness DailyStrength Plaquenil ingredientsPlaquenil help with fatigueChloroquine treatment for vivax malariaHydroxychloroquine side effectsChloroquine synthesis slideshare According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Anxiety and Plaquenil Has anyone experienced mood. - LUPUS UK. Plaquenil and dizziness? Updated. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Fever that happens while in or after coming back from the malaria area. What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. The way I understand it the plaquenil causes some CNS irritability. I think I have a little of it but I will just hang in there cause I had my dosage increased from 200 to 400 and saw results starting after 1 month. For me the relief of some of the symptoms has been very slight improvement that has increased slowly over time.