Excessive production of melanin is responsible for this condition. Hyperpigmentation can occur on almost any part of the body, including the face, neck, hands, arms and legs. Chloroquine ireland Hydroxychloroquine dose adjustment Drug reactions in plaquenil The home remedies for hyperpigmentation of skin involve a few natural ingredients that are easily available and highly effective. The ingredients used in hyperpigmentation natural treatment are enlisted below Raw potatoes; Lime or Lemon; Turmeric powder and lime juice; Vinegar of apple cider; Red onions; Aloe Vera leaves; Cucumbers; Peel of Orange; Almonds Oct 25, 2019 Top 13 Natural Home Remedies For Pigmentation On Face. These are 13 natural home remedies for pigmentation on face which you can do to get rid of pigmentation 1. Papaya Juice. Papaya includes the enzyme papain which may be used for the skin exfoliation. This kind of enzyme is also essential in treating arthritis and digestive disorders. Besides, papaya is found to have high contents of antioxidant nutrients like carotene, vitamin C, vitamin B and flavonoids. Treatment with HCQ was discontinued definitively because of skin pigmentation in 2 patients who reported a gradual incomplete fading of hyperpigmentation. Among patients who continued HCQ treatment n = 22, an improvement in pigmented lesions was reported in 6, despite the maintenance of a similar daily dose of HCQ. External factors like excessive sun exposure, skin injury, burning, emotional stress or contact with certain chemicals can also cause hyperpigmentation. The root cause of excess melanin production is generally attributed to internal factors like hormonal changes in the body, pregnancy and various health problems. Home remedies plaquenil hyperpigmentation Hydroxychloroquine-Associated Hyperpigmentation. - PubMed Central PMC, Top 13 Home Remedies for Pigmentation on Face Plaquenil medication side effectsChloroquine and proguanil anti malaria tabletsChloroquine hydrochloride dose Home Remedies For Pigmentation. These home remedies will not help fade the pigmentation and spots completely. However, they can help improve their appearance and make them less apparent. These remedies take time to show results, so you need to be patient. If your pigmentation and spots are not caused by any medical issues, you may try these home remedies. 1. Apple Cider Vinegar Home Remedies for Pigmentation How To Reduce Dark Spots. Hydroxychloroquine-Induced Pigmentation in Patients With.. How To Get Rid Of Hyperpigmentation – 18 Home Remedies. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Treatment consisted of discontinuing HCQ, which led to the gradual decrease in hyperpigmentation of lesions within several months 5,6. Although there is evidence that both melanin and iron deposits can be present within the dermis in hyperpigmented lesions induced by HCQ 1, the exact mechanism of hyperpigmentation is unknown 7. Oct 30, 2019 Evidence indicates that two natural ingredients, Vitamin C and soy extract, are effective in treating hyperpigmentation. Some purported at-home remedies, such as apple cider vinegar, are ineffective and may instead cause severe irritation when applied to the skin.