I was diagnosed with discoid lupus 18 years ago and was prescribed Plaquenil, which I have taken since then. In October 2012, I was also diagnosed with Sjogrens Syndrome but, as I was already taking Plaquenil, was advised the treatment was the same for Sjogrens. Should i take plaquenil in the morning or night Can plaquenil cause gout Generic pill hydroxychloroquine Retinal deposits plaquenil infared imaging Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis. Hydroxychloroquine therapy has not been associated with liver function abnormalities and is an extremely rare cause of clinically apparent acute liver injury. Find information about common, infrequent and rare side effects of Hydroxychloroquine Oral. From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. At a recent medical with my doctor, blood tests were taken and I had a call a couple of days later telling me to stop taking g Plaquenil immediately as I have a very low white cell count and that it is sometimes a side effect of Plaquenil. Hydroxychloroquine cause low wbc Will you have White blood cell count decreased with Plaquenil., Hydroxychloroquine - LiverTox - NCBI Bookshelf Side effects of chloroquine phosphate tabletsMethotrexate and plaquenil for rheumatoid arthritis Very rare presentation of hydroxychloroquine toxicity. CASE PRESENTATION 36 year old female presented with fever, malaise, chills and a lip rash for 3 days past history included eosinophilic fasciitis being treated with methotrexate for 2 years which was stopped due to intolerence 3 weeks ago and she was started on hydroxychloroquine 300mg daily. Investigation revealed WBC 300. Hydroxychloroquine induced profound neutropenia with s.. Common and Rare Side Effects for Hydroxychloroquine Oral. Hydroxychloroquine Plaquenil. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. Medical use. Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Dugan on plaquenil and low wbc This drug can effect the bone marrow and make the white blood count and platelets low. Your doctor may want to stop this medication, but don't stop it till you talk to the doctor. Good luck!