Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Chloroquine side effect Plaquenil cause anemia Maqular degeneration plaquenil May 12, 2016 Plaquenil can prove toxic to the retina, threatening the vision. Regular eye examinations are essential for those patients taking plaquenil because over time the retina can become damaged beyond repair. Regular medical monitoring is the only way to ensure that toxicity is not occurring. Often a physician prescribes a medication with known side effects because the medication's benefits are seen to outweigh those side effects. Still, the possible side effects need to be monitored. Regular eye exams give your eye care professional a chance to help you correct or adapt to vision changes and provide you with tips on caring for your eyes. When to have an eye exam Several factors may determine how frequently you need an eye exam, including your age, health and risk of developing eye problems. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil eye exam same as regular eye exam My Take on New Ocular Screening Guidelines for Plaquenil., Plaquenil regimen requires monitoring for eye problems. Generic for hydroxychloroquine 200 mgPlaquenil and dry eyesChloroquine base molecular weightPlaquenil and bursitisChloroquine resistant malaria in pregnant Apr 20, 2011 In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. Testing included a comprehensive eye exam that consisted of an assessment of the posterior segment with careful evaluation of associated macular changes or signs of retinal disease. 4 Baseline fundus photography was considered as an optional test. New Plaquenil Guidelines. Eye exam - Mayo Clinic. Plaquenil Side Effects on Your Eyes and Vision. I can't say for sure if plaquenil would slow down or halt progression of RA, but I've been told methotrexate does. As for a comparison between the two, it's difficult to say. As long as you have regular eye doctor appointments and blood tests to check for adverse reactions, you'd be able to catch anything bad ahead of time before significant. I was told from the start by my rheumatologist I would have to have eye exams including visual field exams every six months due to the plaquenil therapy. My first two exams did include these tests. But my next six month appointment is coming up, and they told me I didn't need the visual field test this time so the appointment would be shorter. Feb 27, 2012 It depends on the exam. Walmart offers an eye exam for $39.00, but that just tests your vision to see if you need glasses. If you want a good exam where they dialate and look inside your eyes, then $80-120 is the norm. I pay $95.00 and get a very thorough exam for that price.