This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. What should a nurse monitor when taking hydroxychloroquine Plaquenil ibuprofen interaction Plaquenil and arthritis Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Chloroquine treatment influences proinflammatory cytokine levels in systemic lupus erythematosus patients. Wozniacka A1, Lesiak A, Narbutt J, McCauliffe DP, Sysa-Jedrzejowska A. Author information Systemic lupus erythematosus SLE is an autoimmune disease with a complex pathogenesis. Antimalarials for lupus include chloroquine Aralen, used off-label ; hydroxychloroquine Plaquenil BLyS-specific inhibitors or monoclonal antibodies MAbS Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine for lupus Compare Plaquenil vs Chloroquine -, Chloroquine treatment influences proinflammatory cytokine. T off plaquenilHow plaquenil helps lupus ph levelsFalciparum gb4 chloroquine ic50Long term side effects of hydroxychloroquineSub for plaquenil Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious Chloroquine - Wikipedia. Lupus Medications Steroids, NSAIDs, and More. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Chloroquine can be used to kill malaria parasites living in red blood cells but the medication may not necessarily be efficient at killing these parasites in other body tissues. Doctors often prescribe this medication as part of certain treatment plans for lupus and other immune system diseases. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition. Hydroxychloroquine Plaquenil Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria.