One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil depressed Can plaquenil reduce your spleen size Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Do you take Plaquenil for Rheumatoid Arthritis? Plaquenil Side-Effects. What is Plaquenil and how does it affect your eyes? Plaquenil Hydroxychloroquine is a medication that is used often to treat conditions such as Rheumatoid Arthritis, Lupus Sarcoidosis, and additional autoimmune disorders. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil adverse effect on retina Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Hydroxychloroquine how do you take itCan plaquenil cause swelling of mouthWhich hydroxychloroquine manufacturer not workCan plaquenil cause alopeciaRheumatology.org plaquenil Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. The Risk of Retinal Toxicity with Plaquenil. Plaquenil. Ocular side effects of anti-rheumatic medications what a.. Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Hydroxychloroquine, an anti-malarial medication, is useful in treating several forms of malaria as well as various rheumatologic diseases, such as rheumatoid arthritis RA, 1 systemic lupus erythematosus SLE and dermatologic conditions. 2 Retinal toxicity is a well-known adverse effect associated with the use of chloroquine and.