Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Hydroxychloroquin eye Plaquenil and easy bruising Plaquenil mg kg eyewiki Ingredients hydroxychloroquine Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Sometimes these manifestations can be linked to more serious lenticular, optic nerve or retinal findings, and this should be reported to the patient’s primary care physician in a timely manner. Report ocular side effects to the National Registry of Drug-Induced Ocular Side Effects at 1. Hollander DA, Aldave AJ. Plaquenil is an extremely safe medication but retinal and corneal side effects are possible. Unfortunately, the retinal side effects are largely irreversible and can lead to vision loss. So, it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Side effects of plaquenil on the cornea Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, When ‘Collateral Damage’ Strikes the Cornea Plaquenil pregnancy category Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Plaquenil Related Eye Problems - Fraser Eye. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 Jun 13, 2019 Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision.