Chloroquine chemotherapy

Discussion in 'Chloroquine Drug' started by KraGovWWW, 22-Feb-2020.

  1. paranoya Guest

    Chloroquine chemotherapy


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

    Hydroxychloroquine scarring alopecia Plaquenil and wound healing Chloroquine in cancer therapy a double edged sword of autophagy

    The present article reviews the several known direct and indirect effects of different doses of Chloroquine on cancer and how those effects may indicate that a fine tuning of the dose/schedule of Chloroquine administration versus chemotherapy may be critical to obtain an adjuvant effect of Chloroquine in anti-cancer treatments. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Our study demonstrates that via to date unreported effects, chloroquine is an effective adjuvant therapy to chemotherapy, offering more efficient tumor elimination and improved cure rates. Chloroquine should be further explored in the clinical setting as its success may help to more rapidly improve the poor prognosis of patients with pancreatic.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine chemotherapy

    Chloroquine With Taxane Chemotherapy for Advanced or., Chloroquine - Wikipedia

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  4. This trial is looking at adding hydroxychloroquine to chemotherapy for people with small cell lung cancer that has spread. Lung cancer that has spread is called advanced lung cancer. Recent research shows that a drug called hydroxychloroquine HCQ might help chemotherapy work better. It does this.

    • A trial of chemotherapy and hydroxychloroquine for small cell..
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    Autophagy-deficiency exacerbates injuries in organs such as the brain, liver, heart, and hematopoietic cells ; thus, the combination use of chemotherapy with chloroquine may unexpectedly worsen the function of these organs. For example, most chemotherapies often cause bone marrow depression, and the addition of chloroquine may worsen this. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis.

     
  5. mok Guest

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  6. Nikita XenForo Moderator

    Chloroquine And Hydroxychloroquine Toxicity - StatPearls. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I.

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