Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Does plaquenil compromise the immune system How does plaquenil help Plaquenil liver side effects Hydroxychloroquine and reduction of metastasis Hi! I think Plaquenil is the cause of my extreme fatigue too. I am not anemic at this time and I get exhausted just trying to get through the day. I have also been on Plaquenil about three months. All of my arthritis swelling and pain are gone, but the fatigue will not let up! Hope things change for you. I’m sorry to hear about the negatives regarding Plaquenil. It has been a miracle drug for me with the pain from RA. I only recently found out that this was a drug used to treat malaria, and that it can cause problems with eyesight. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Does plaquenil cause headaches Nausea from Plaquenil, etc" Lupus Community - Support Group, Medication Triggers in Autoimmune Migraineurs Hydroxychloroquine new indicationsAshwagandha and plaquenilChloroquine brain tumorChloroquine phosphate uses in hindi Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Health Issues - Drug Interactions / Side Effects Plaquenil.. PLAQUENIL is not recommended for malaria prophylaxis in geographic areas where chloroquine resistance occurs. PLAQUENIL does not prevent relapses of P. vivax or P. ovale because it is not active against the hypnozoite forms of these parasites. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. I take plaquenil for RA, MCTD, etc. it worsens headache that are daily 24/7. Most drugs I took for AI diseases, prescribed by my rheumy, worsened headaches. The headaches range from mild to migraine, to dizzying. My neurologist is now evaluating me for a cerebral spinal fluid leak which can cause positional headache.