Please review the following URL and make sure that it is spelled correctly. Plaquenil, hydroxychloroquine (HCQ), is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory and autoimmune diseases. Maculopathy from plaquenil Side effects of stopping plaquenil cold turkey Plaquenil is taken by mouth with food or milk to prevent stomach problems. When taking this medication, some patients may experience upset stomach, nausea, loss of appetite, headaches or dizziness. Sometimes, taking high doses or long-term treatment of Plaquenil can lead to vision problems. A rare side effect of Plaquenil involves visual changes or possible loss of vision—the side effect that is most worrisome for patients. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. Aug 29, 2014 Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Plaquenil eye issues Will you have Vision problems with Plaquenil - eHealthMe, Taking Plaquenil for Rheumatoid Arthritis Chloroquine pharmacologyHydroxychloroquine dose for malaria Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. The Risk of Retinal Toxicity with Plaquenil. What can Hydroxychloroquine Plaquenil do to my eyes?. An eye exam is recommended at the start of treatment to detect any existing vision problems; follow-up tests are needed to catch retinal damage in the earliest stages, before symptoms appear. If found later, damage to the eye may be irreversible, even if the medication is stopped. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. A few years ago my eye doctor noticed an issue on the exam, and I noticed peripheral vision damage and glare issues. He immediately same day called my rheumatologist, who took me off plaquenil. My eye doc said it was the first case he had seen where there was an effect.