Plasmodium falciparum chloroquine resistance transporter

Discussion in 'Chloroquine Pills' started by madPanda, 09-Mar-2020.

  1. Sergey75 New Member

    Plasmodium falciparum chloroquine resistance transporter


    This score cannot be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein. This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. This subsection of the Names and taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry.

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    Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. In addition to its utility in the diagnosis of malarial infection, PCR appeared to be a must for epidemiological surveys focused on Plasmodium falciparum with resistance to aminoquinolines, as assessed by the detection of point mutations in the P. falciparum chloroquine-resistance transporter pfcrt and P. falciparum multidrug-resistance. Investigation of the Plasmodium falciparum Food Vacuole through Inducible Expression of the Chloroquine Resistance Transporter PfCRT

    This is known as the 'taxonomic identifier' or 'taxid'. This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. Cyclic redundancy and other checksums Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)) AF030694 Genomic DNA Translation: AAF26926.1AF233064 m RNA Translation: AAF60271.1AF233065 m RNA Translation: AAF60272.1AF233066 m RNA Translation: AAF60273.1AF233067 m RNA Translation: AAF60274.1AF233068 m RNA Translation: AAF60275.1AF495376 Genomic DNA Translation: AAO85506.1AF495377 Genomic DNA Translation: AAO85507.1AF495378 Genomic DNA Translation: AAO85508.1AY651315 m RNA Translation: AAU00067.1AF468006 m RNA Translation: AAL75580.1DQ156107 m RNA Translation: AAZ81606.1DQ156108 m RNA Translation: AAZ81607.1DQ156109 m RNA Translation: AAZ81608.1DQ533840 m RNA Translation: ABF82363.1AY254700 m RNA Translation: AAP79044.1AF030694 Genomic DNA Translation: AAF26926.1AF233064 m RNA Translation: AAF60271.1AF233065 m RNA Translation: AAF60272.1AF233066 m RNA Translation: AAF60273.1AF233067 m RNA Translation: AAF60274.1AF233068 m RNA Translation: AAF60275.1AF495376 Genomic DNA Translation: AAO85506.1AF495377 Genomic DNA Translation: AAO85507.1AF495378 Genomic DNA Translation: AAO85508.1AY651315 m RNA Translation: AAU00067.1AF468006 m RNA Translation: AAL75580.1DQ156107 m RNA Translation: AAZ81606.1DQ156108 m RNA Translation: AAZ81607.1DQ156109 m RNA Translation: AAZ81608.1DQ533840 m RNA Translation: ABF82363.1AY254700 m RNA Translation: AAP79044.1 This subsection of the 'Entry information' section provides a mnemonic identifier for a Uni Prot KB entry, but it is not a stable identifier. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'. This subsection of the Names and taxonomy section shows the unique identifier assigned by the NCBI to the source organism of the protein.

    Plasmodium falciparum chloroquine resistance transporter

    Chloroquine Resistance in Plasmodium falciparum - microbewiki, Plasmodium falciparum Chloroquine-Resistance Transporter.

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  3. Juge, N. et al. Plasmodium falciparum chloroquine resistance transporter is a H +-coupled polyspecific nutrient and drug exporter. Proc. Natl Acad. Sci. USA 112, 3356–3361 2015.

    • Structure and drug resistance of the Plasmodium falciparum..
    • Investigation of the Plasmodium falciparum Food Vacuole..
    • Plasmodium falciparum chloroquine resistance transporter is a..

    We obtained 78 human blood samples from areas in Haiti with high transmission of malaria and found no drug resistance–associated mutations in Plasmodium falciparum chloroquine resistance transporter and Kelch 13 genes. We recommend maintaining chloroquine as the first-line drug for malaria in Haiti. Sep 30, 2015 Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P. Sep 25, 2009 The Chloroquine Resistance Transporter PfCRT was originally identified because mutations in this protein confer chloroquine resistance in the human malaria parasite, Plasmodium falciparum. However, the mechanism by which they do so has been the subject of ongoing debate. Martin et al. p.

     
  4. Mir-Domen Well-Known Member

    It should not be consumed by women who want to conceive, or are already pregnant. Medication Cautions in Macular Degeneration - AMDF Celebrex and lisinopril - MedHelp Hydroxychloroquine Oral Route Side Effects - Mayo Clinic
     
  5. sopli42 New Member

    13 mg/kg (10 mg/kg base), not to exceed 800 mg (620 mg base) followed by 6.5 mg/kg (5 mg/kg base), not to exceed 400 mg (310 mg base), at 6 hours, 24 hours and 48 hours after the initial dose. Hydroxychloroquine Dosage Guide with Precautions - Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  6. 1000links Moderator

    What can Hydroxychloroquine Plaquenil do to my eyes? Jan 18, 2019 Hydroxychloroquine Plaquenil is a very useful drug to treat Rheumatoid Arthritis and Lupus but it can have some significant visual side effects unless properly dosed and monitored. What can Hydroxychloroquine Plaquenil do to my eyes?

    Hydroxychloroquine Side Effects, Dosage, Uses, and More