Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Chloroquine injection route Is atovaquone proguanil a chloroquine Hydroxychloroquine lupus anticoagulant Hydroxychloroquine with or without food Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Hydroxychloroquine use in children younger than 7 may be limited by the difficulty in obtaining satisfactory evaluation of color vision in this age group. Therefore, children taking HCQ should receive an annual ophthalmologic examination. Other rare side effects include changes in skin pigmentation and cardiomyopathy diseases of the heart muscle. Monthly ophthalmic exams are recommended for doses of ethambutol exceeding 15 mg/kg/day. Fluoroquinolones are associated with side effects not seen in other classes of antibiotics. Topical administration may cause precipitates in the cornea and, possibly, uveitis. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Ophthalmologic exam for plaquenil use Plaquenil Hydroxychloroquine Sulfate, Drug spotlight on hydroxychloroquine Lupus Foundation of. Long term plaquenil use and electrolyte imbalanceCommon side effects of plaquenilHow long to take plaquenil for lupusPlaquenil and cirrhosisNatural remedies for mold in your body heavy metals chloroquine I have been taking plaquenil for a little over 10 years and getting eye exams regularly. Suddenly I'm experiencing eye problems blilnd spots. I have stopped taking plaquenil, but now I'm being told by doctors that the damage is not necessarily reversible especially if you have taken it for a long time. Has anyone experienced plaquenil toxicity with damage to eyes?. Rx Side Effects New Plaquenil Guidelines and More - American.. Eye screening for patients taking hydroxychloroquine Plaquenil. All individuals starting Plaquenil treatment should have a baseline ophthalmologic examination within the first year. If the initial ophthalmologic examination is normal and the person is considered low risk, re-testing need not occur for five years. It is recommended that high-risk patients have annual eye examinations. Or shorter - up to 200 mg Plaquenil daily; Women with lupus who are AT OR BELOW their ideal body weight should go by these dosing rules 135 lbs. or more, any height - up to 400 mg Plaquenil daily; 102 lbs. to 134 lbs. - up to 300 mg Plaquenil daily; 101 lbs or less - up to 200 mg Plaquenil daily; A lupus patient explains her changes in vision A baseline ocular examination is recommended within the first year of starting PLAQUENIL. The baseline exam should include best corrected distance visual acuity BCVA, an automated threshold visual field VF of the central 10 degrees with retesting if an abnormality is noted, and spectral domain ocular coherence tomography SD-OCT.