It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. What is hydroxychloroquine sulphate used for Off label plaquenil I also take Methotrexate, along with Plaquenil plus many others and I don't drink any alcohol. Then again, this is an individual decision. I would run it by my doctor and see if they thought it was ok. You then could either drink a little wine, or abstain. I have read where a glass of wine OCCASIONALLY wouldn't hurt. Alcohol interaction warning. Alcohol abuse can damage your liver, which can affect how hydroxychloroquine works in your body. Avoid alcohol while taking this medication. The study is based on acetaminophen / dextromethorphan / doxylamine / pseudoephedrine and hydroxychloroquine sulfate the active ingredients of Nyquil and Plaquenil, respectively, and Nyquil and Plaquenil the brand names. Other drugs that have the same active ingredients e.g. generic drugs are not considered. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Can you drink alcohol with hydroxychloroquine Hydroxychloroquine Oral Route Proper Use - Mayo Clinic, Hydroxychloroquine Side Effects, Dosage, Uses, and More Chloroquine malaria resistancePlaquenil metabolismDrug quinine and chloroquineThe trade name of chloroquine isMalaria tablets chloroquine and proguanil side effects This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine. What should I watch for while using this medicine? Hydroxychloroquine tablets - Cleveland Clinic. Nyquil and Plaquenil drug interactions - eHealthMe. Plaquenil and Alcohol Interaction - Alcohol Explained. Back when it was time for me to add a DMARD, alcohol was one of the factors in my choice of hydroxychloroquine instead of methotrexate. I enjoy beer almost as much as Coca-Cola! and I usually drink 2 pints per week sometimes more in the summertime. You should also tell your doctor if you drink large amounts of alcohol. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. Tell your doctor if you have or have ever had liver disease, psoriasis, porphyria or other blood disorders, G-6-PD deficiency, dermatitis skin inflammations, or if you drink large amounts of alcohol. tell your doctor if you have ever had vision changes while taking hydroxychloroquine, chloroquine Aralen, or primaquine.