Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Chloroquine bull's eye maculopathy guidelines Plaquenil affect immune system The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. TB disease is treated by taking several drugs as recommended by a health care provider. If a person does not have TB disease, but has TB bacteria in the body, then latent TB infection is diagnosed. The decision about taking treatment for latent TB infection will be based on a person’s chances of developing TB disease. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Should you check for tb before taking plaquenil Stopping Plaquenil and Cellcept when on Antibiotics, Protecting your eyesight when taking Plaquenil Lupus. Hydroxychloroquine monitoring guidelinesPlaquenil buy onlineWhat is chloroquine chemoprophylaxis Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Plaquenil Uses, Dosage & Side Effects -. Fact Sheets Testing & Diagnosis Testing for Tuberculosis.. MEDICATION GUIDE XELJANZ ZEL’ JANS’ tofacitinib What is.. No haven't heard about blood tests for Plaquenil but yes to the eye tests. I've been taking Plaquenil for about 10 years now. But come to think of it I do think the specialist checked my blood early on so maybe if it is going to affect you it is in the early stages of taking it? Ones to check for any changes. You will continue to be screened every year until you stop taking hydroxychloroquine. Possible retinopathy If there is an abnormality found in any one test it means there is a possibility of there being signs of hydroxychloroquine retinopathy. If the abnormal test is the visual field test, you may be Remember, any patient who is at a high risk for Plaquenil toxicity should be examined on an annual basis following the baseline exam. The goal of monitoring/screening is to identify early macular damage prior to irreversible vision loss or even before visible signs of bull’s eye maculopathy.