In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. How does plaquenil help inflammation K63 ub after chloroquine Plaquenil overdose 1950s chloroquine resistance greater mekong subregion Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Aug 14, 2013 Most commonly, its use can result in hyperpigmentation of the forehead, hard palate, forearms, and shins 2, 3 ; it can also cause pigmentation that appears on the cheek mucosa and nails 6, 11. The development of hydroxychloroquine-associated cutaneous dyschromia is not so rare and can present as black. Download PDF Many systemic medications may cause retinal toxicity. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Hydroxychloroquine-induced pigmentation Prevalence and risk factors of hyperpigmentation induced by., Hydroxychloroquine-induced pigmentation in patients with. Methotrexate plaquenil alcoholEffects of plaquenil on visionChloroquine in hepatic amoebiasisEffects of hydroxychloroquine on taste Blue–grey pigmentation of the skin affects up to 25% of patients taking hydroxychloroquine, especially where there has been bruising. Transverse pigmented nail bands and mucosal pigmentation have also been reported. Rashes may occur in up to 10% of patients, most commonly morbilliform or psoriasiform. Hydroxychloroquine DermNet NZ. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Skin Pigmentation with Hydroxychloroquine Plaquenil — Donovan Hair Clinic. IMPORTANCE Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. The previous ophthalmological examination had been made 3 years before and there was no sign of retinal involvement. A skin biopsy was performed and showed pigment deposition in superficial dermis with haemosiderin characteristics—Perls Prussian staining was positive for iron and Fontana-Masson staining was negative for melanin. In 12 of 41 29% of the hydroxychloroquine users, we conclude a hydroxychloroquine-induced pigmentation. There were 11 women and one man with a mean age of 43 years and all of them were systemic.