Hydroxychloroquine-induced pigmentation

Discussion in 'Northwest Pharmacy Canada' started by sergey_k, 17-Mar-2020.

  1. ana_vase New Member

    Hydroxychloroquine-induced pigmentation


    In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent.

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    Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Aug 14, 2013 Most commonly, its use can result in hyperpigmentation of the forehead, hard palate, forearms, and shins 2, 3 ; it can also cause pigmentation that appears on the cheek mucosa and nails 6, 11. The development of hydroxychloroquine-associated cutaneous dyschromia is not so rare and can present as black.

    Download PDF Many systemic medications may cause retinal toxicity. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended.

    Hydroxychloroquine-induced pigmentation

    Prevalence and risk factors of hyperpigmentation induced by., Hydroxychloroquine-induced pigmentation in patients with.

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  6. Blue–grey pigmentation of the skin affects up to 25% of patients taking hydroxychloroquine, especially where there has been bruising. Transverse pigmented nail bands and mucosal pigmentation have also been reported. Rashes may occur in up to 10% of patients, most commonly morbilliform or psoriasiform.

    • Hydroxychloroquine DermNet NZ.
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    • Skin Pigmentation with Hydroxychloroquine Plaquenil — Donovan Hair Clinic.

    IMPORTANCE Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. The previous ophthalmological examination had been made 3 years before and there was no sign of retinal involvement. A skin biopsy was performed and showed pigment deposition in superficial dermis with haemosiderin characteristics—Perls Prussian staining was positive for iron and Fontana-Masson staining was negative for melanin. In 12 of 41 29% of the hydroxychloroquine users, we conclude a hydroxychloroquine-induced pigmentation. There were 11 women and one man with a mean age of 43 years and all of them were systemic.

     
  7. kkapitan User

    One form of the condition, known as CREST syndrome, classically results in calcium deposits, Raynaud's syndrome, esophageal problems, thickening of the skin of the fingers and toes, and areas of small dilated blood vessels. Scleroderma Management and Treatment Cleveland Clinic Being tested for possible lupus or scleroderma? lupus Best Home Remedies For Scleroderma
     
  8. Magistr Yoda Well-Known Member

    Rheumatoid arthritis can’t be cured, but joint pain and other symptoms can be managed. What’s It Worth? The Pros and Cons of Methotrexate. Rheumatoid Arthritis Drug Treatments Pros and Cons Everyday Health How long did Plaquenil/Hydroxychloroquine take.
     
  9. kipekha User

    Agua con vinagre y bicarbonato, un milagro para la salud. El agua con vinagre y bicarbonato se han utilizado tradicionalmente de múltiples maneras para todo tipo de remedios de salud y belleza. Son dos productos eficaces, económicos y fáciles de conseguir. Además de usarse como limpiadores del hogar o para lavar el cabello de forma natural, en este artículo explicamos cómo esta combinación puede resultar como un remedio de salud para prevenir.

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  10. mKostya New Member

    Hydroxychloroquine DermNet NZ Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Hydroxychloroquine is rapidly absorbed from the gastrointestinal tract, and steady-state concentrations are reached after 4–6 weeks; 45% of hydroxychloroquine binds to plasma proteins that are deposited in tissues such as the liver, spleen, kidney, and lung.

    Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening