Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil affect immune system Plaquenil for chilblains This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. Blurred vision or other vision changes. chest discomfort, pain, or tightness. cough or hoarseness. dark urine. decreased urination. defective color vision. diarrhea. difficulty breathing. difficulty seeing at night. dizziness or fainting. fast, pounding, uneven heartbeat. feeling that others are watching you or controlling your behavior What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Not hungry. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil vision side effects The Risk of Retinal Toxicity with Plaquenil, Plaquenil Side Effects - GoodRx Plaquenil full prescribing informationPlaquenil screening 2018 Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Indications, Side Effects, Warnings -. Plaquenil Side Effects Common, Severe, Long Term -. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. A rare side effect of Plaquenil involves visual changes or possible loss of vision—the side effect that is most worrisome. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs.