Chloroquine irreducible complexity

Discussion in 'Plaquenil' started by lachty, 23-Feb-2020.

  1. hellevil Moderator

    Chloroquine irreducible complexity


    Even if Behe had been wrong, the critics’ extreme incivility would have been unscholarly and inappropriate. You get no resistance to chloroquine whatsoever unless at least two mutations are present to begin with. You might be able to get some cumulative selection after that, where successive mutations improve resistance up to a certain point.

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    It has been reported that resistance to this drug involves the appearance of at least two amino acid changes. Behe argues that these need to be essentially simultaneous in appearance, and coins a term the Chloroquine Complexity Cluster to stand for events that involve leaps of two simultaneous mutational changes. Irreducible complexity is not a watertight argument for the involvement of intelligence in the formation of biological systems. It's possible that an irreducible system could be a simplification of a more complex one; a backpack can still hold things if you remove the straps, zipper, and exterior pockets. Oct 06, 2009 The titles of two recent science news articles caught my attention, “More ‘Evidence’ of Intelligent Design Shot Down by Science” and “Intelligent Design ‘Evidence’ Unproven by Real Science.”1 The evidence in question is a molecular machine.

    Behe reasonably inferred that chloroquine resistance requires multiple mutations. His critics misunderstood his argument and thought this inference was a crucial plank in his reasoning. But it now turns out that the position Behe’s critics attributed to him, and then railed against, was itself correct. It is, however, by definition a multimutation feature.

    Chloroquine irreducible complexity

    Philosophical-ish Objections to Intelligent Design A., Irreducible complexity - What is it?

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  6. Apr 02, 2019 Readers may recall the concept of a “chloroquine complexity cluster” CCC, introduced in Michael Behe’s second book, The Edge of Evolution Behe, 2007. Behe observed that resistance of the malarial parasite to chloroquine is rare, arising only once in every 10 20 cells of the parasite Plasmodium falciparum. Behe argued that the.

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    Jun 05, 2007 He invents a new metric, the CCC, or "chloroquine complexity cluster". This is the probability of evolving a fairly simple trait in the malaria parasite, resistance to a compound called chloroquine. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. The Edge of Evolution in no way backs away from the argument for irreducible complexity. Behe makes this very clear in the book And now the problem of its irreducible complexity has been enormously compounded. Let's reconsider the mousetrap--the paradigm of irreducible complexity I discussed in Darwin's Black Box.

     
  7. Flux_2514 Guest

    Warfarin, a vitamin K antagonist, is used to prevent thrombotic events in conditions such as atrial fibrillation (AF). Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Hydroxychloroquine Side-effects, uses, time to work
     
  8. Michil User

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. Medicines for the Prevention of Malaria While Traveling - Chloroquine. Chloroquine diphosphate salt Sigma-Aldrich Hydroxychloroquine Oral Uses, Side Effects, Interactions.
     
  9. grunge270 Well-Known Member

    Prescribing Guide - Standard Control The information contained in this Prescribing Guide - Standard Control and its appendices is provided solely for the convenience of medical providers. We do not warrant or assure accuracy of such information nor is it intended to be comprehensive in nature. This Prescribing Guide - Standard Control is not intended

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  10. Alex_777 New Member

    Hydroxychloroquine Advanced Patient Information - Sep 13, 2019 Hydroxychloroquine may cause muscle and nerve problems. Check with your doctor right away if you have muscle weakness, pain, or tenderness while using hydroxychloroquine. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors.

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